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  • Causes of increased D-dimer - acute care testing

    The most frequent diagnosis in this cohort of patients was infection. This was the cause of positive D-dimer test for 257 (15.6 %) patients. Other non-VTE diagnoses included: syncope, 155 (9.4 %) patients; heart failure, 146 (8.9 %) patients; trauma, 135 (8.2 %) patients; and cancer, 95 (5.8 %) patients. In total, 31 different non-VTE final ...

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  • Never ignore extremely elevated D-dimer levels: they

    Although D-dimer testing has a reputation for being very non-specific, an extremely elevated D-dimer is uniquely associated with severe disease, mainly including VTE, sepsis and/or cancer. These results suggest that, even if sharply elevated D-dimers are a seemingly solitary finding, clinical suspic …

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  • D-Dimer - Health Encyclopedia - University of

    If you are having significant formation and breakdown of blood clot in your body, your D-dimer may be elevated. A negative D-dimer test means that a blood clot is highly unlikely. A positive D-dimer test doesn't mean that you have a clot. There may be other reasons it is positive.

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  • D-dimer test, normal D-dimer level and elevated D

    2019-1-10 · A D-Dimer test is said to be positive when its levels are elevated. This indicates towards excessive blood clot formation and degradation happening simultaneously somewhere in the body even though this test does not pinpoint the location of the abnormality.

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  • What Does an Elevated D-Dimer Test Mean and What

    D-dimer level is one of the measures used in patients to detect thrombosis. Studies have reported an increase in D-dimer and fibrinogen concentrations in the early stages of COVID-19 disease a 3 to 4-fold rise in D-dimer levels is linked to poor prognosis. In addition, underlying diseases such as di …

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  • The D-Dimer Test: What You Should Know - Verywell

    The normal amounts for D-dimer in the blood should be around 0.5 mg/l of blood or 500 ng/ml of blood. A normal D-dimer test result will reveal a negative result, which indicates that thrombosis has not occurred. People who yield negative or normal D-dimer test results are most likely not suffering from any acute medical condition or disorder ...

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  • D-dimer test: MedlinePlus Medical Encyclopedia

    2021-6-9 · A positive test may be caused by other factors, and you may not have any clots. D-dimer levels can be positive due to: Pregnancy; Liver disease; Recent surgery or trauma; High lipid or triglyceride levels; Heart disease; Being over 80 years old; This makes the test mostly useful when it is negative, when many of the above causes can be ruled out.

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  • D-dimer test, normal D-dimer level and elevated D

    2021-6-24 · A D-dimer test is a blood test that can be used to help rule out the presence of a serious blood clot. When you get a cut, your body takes a bunch of steps to make your blood clump up. It’s a ...

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  • The D-Dimer Test: What You Should Know - Verywell

    2020-3-31 · An elevated level of D-dimer has a few causes. Serious blood clotting problems, such as pulmonary embolism, which is life threatening, can result in high levels of D-dimer. A patient with high D-dimer levels may also have disseminated intravascular coagulation (DIC), another serious condition that prevents blood from clotting as it should.

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  • Why a Positive D-Dimer Is Not Always a Blood Clot »

    D-dimer is the breakdown product; derived from action of plasmin; a clot degrading enzyme, and this works as primary diagnostic tool in various diseases such as; deep venous thrombosis (DVT), systemic illness and cancers. Here D stands for domain and is written as D-dimer or d-dimer [4,5].

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  • D-Dimer Test For Blood Clots: Normal Range, Elevated

    The normal amounts for D-dimer in the blood should be around 0.5 mg/l of blood or 500 ng/ml of blood. A normal D-dimer test result will reveal a negative result, which indicates that thrombosis has not occurred. People who yield negative or normal D-dimer test results are most likely not suffering from any acute medical condition or disorder ...

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  • What Causes an Elevation of D-Dimer? - Reference

    2020-12-2 · D-dimer testing is recommended for patients with an ‘unlikely’ PE Wells score (≤ 4 points), with imaging diagnosis methods undertaken if the test results are positive [17, 19]. The revised NICE guidelines support the use of a quantitative D-dimer test, with consideration given to the use of POCT if laboratory facilities are not ...

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  • Positive D-dimer - Breast Cancer - MedHelp

    Hello, I was wondering if anyone had a positive d-dimer test prior to finding out they had breast cancer. I was told that I had a positive d-dimer in January(slightly high). I discovered a lump in my breast a week ago. I read that they can be related.

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  • i have high d-dimer results with no blood clot, what

    2020-12-15 · Any number of things: A high d-dimer just means that the body's clotting system has been activated. Of course, clots can do it, but a great many other things - like infections, trauma, cancer, etc - can cause an elevated d-dimer.It is a very unspecific test. It is very hard to tell what could be wrong with simply an elevated d-dimer. It should be interpreted with other tests and evaluations.

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  • What Causes an Elevation of D-Dimer? - Reference

    2020-3-31 · An elevated level of D-dimer has a few causes. Serious blood clotting problems, such as pulmonary embolism, which is life threatening, can result in high levels of D-dimer. A patient with high D-dimer levels may also have disseminated intravascular coagulation (DIC), another serious condition that prevents blood from clotting as it should.

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  • Elevated D-dimer is not always pulmonary embolism ...

    2011-1-1 · Elevated D-dimer, although not specific for AAD is a highly sensitive marker of the condition. D-dimer has high negative predictive value and likely rules out AAD. High index of suspicion should be maintained for the patients with chest pain in ED and D-dimer should be used as screening test …

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  • D Dimer and high levels - Advanced breast cancer -

    2016-11-7 · November 7, 2016 at 2:41 pm. Report. A d-Dimer blood test value that is elevated can occur when there is a higher than usual amount of degradation (break-down) of fibrin molecules. Fibrin is often associated with the formation of blood clots and/or blood vessels, and the d-Dimer can be elevated in DVT or PE, as well as other conditions ...

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  • Patients with markedly elevated D-dimer who do not

    2021-1-29 · Results Eighty-five patients fulfilled our inclusion criteria. The likely causes of their very high D-dimer were infection (n=35, 41.2%), cardiovascular disease (n=12, 14.1% including two patients with previously undiagnosed aortic dissection), surgery or trauma (n=12, 14.1%), new or active cancer (n=9, 10.6% comprising six new cancers and three patients with cancers diagnosed previously that ...

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  • D-Dimer in Aortic Dissection Workup - emDOCs.net ...

    The normal amounts for D-dimer in the blood should be around 0.5 mg/l of blood or 500 ng/ml of blood. A normal D-dimer test result will reveal a negative result, which indicates that thrombosis has not occurred. People who yield negative or normal D-dimer test results are most likely not suffering from any acute medical condition or disorder ...

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  • D-dimer normal values, Range - Symptoms, Treatment

    2020-12-2 · D-dimer testing is recommended for patients with an ‘unlikely’ PE Wells score (≤ 4 points), with imaging diagnosis methods undertaken if the test results are positive [17, 19]. The revised NICE guidelines support the use of a quantitative D-dimer test, with consideration given to the use of POCT if laboratory facilities are not ...

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  • Point-of-Care Testing for D-Dimer in the Diagnosis of ...

    2014-4-17 · Joined: Feb 2013. Apr 16, 2014 - 9:11 pm. Hey all, I have a question. Does anyone know what an elevated D-Dimer means if there is no evidence of a blood clot? Jason's is very high (2480.0 normal is 0.0-400.0). He was having some chest pain, so they did a test to check for a blood clot but didn't find anything.....

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  • D-Dimer Test: MedlinePlus Medical Test

    2021-6-10 · A D-dimer test is most often used to find out whether you have a blood clotting disorder. These disorders include: Deep vein thrombosis (DVT), a blood clot that's deep inside a vein. These clots usually affect the lower legs, but they can also happen in other parts of the body. Pulmonary embolism (PE), a blockage in an artery in the lungs.

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  • Widely Used Types and Clinical Applications of D

    The i-CHROMA D-Dimer Test (SYCOmed e.K.) is a sandwich immunoassay with a nitrocellulose matrix designed for measuring plasma D-dimers within a working range of 50 to 10,000 ng per mL; the emitted fluorescence is measured with the i-CHROMA Reader. ... In contrast with a negative D-dimer result, a positive D-dimer assay result is nonspecific and ...

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  • The Clinical Usefulness of D-Dimer Testing in Cancer ...

    2021-6-25 · A normal or 'negative' D-dimer result means that the individual tested does not have any acute condition ore disease. A positive D-dimer result depicts the presence of a very high level of fibrin degradation products. It shows that there can be significant blood clot (thrombus) formation and breakdown in the body.

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  • D-Dimer Blood Test in Mumbai - Metropolis Healthcare

    2018-5-25 · D-dimer is one of the protein fragments produced when a blood clot gets dissolved in the body. It is normally undetectable or detectable at a very low level unless the body is forming and breaking down blood clots. Then, its level in the blood can significantly rise. This test detects D-dimer in the blood.

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  • D-dimer - Understand the Test - Lab Tests Online

    2014-7-1 · Background Plasma D-dimer levels have been shown to be high in advanced tumor stage patients and can be used to predict clinical outcome in cancer patients. As most advanced tumor stage patients exhibit asymptomatic metastasis, which contributes to early tumor recurrence after surgery, we hypothesized that plasma D-dimer levels can be used to predict patients with potential metastasis.

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  • D-Dimer: Not Just an Indicator of Venous Thrombosis

    2014-2-6 · Question: I am a 27 year old female who regularly has pain in my arms, legs back and neck. I had a d dimer test done and it was 2500 them had it redone and it was 1900. I have had a chest x ray, MRI and ultrasounds on legs to rule out a blood clot.I do have hypo thyroid and take meds for it. I have also had shingles a few months ago. What could be causing my elevated d dimer

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  • What could be the cause for elevated D dimer values

    2017-10-15 · melissah528. October 16, 2017 at 1:24 pm. Report. A word about D-Dimer - it is a completely non-specific test that indicates any kind of inflammation in your body. It does not mean you have a blood clot. I have had several high D-Dimer tests when I haven't had a blood clot. Simply having a cold can elevate your D-Dimer.

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  • CTs all clear D Dimers Elevated Anxiety High - Blood

    2021-6-15 · A high D-dimer at admission was an independent predictor for mortality in COVID-19 patients from Wuhan. Patients with a D-dimer ≥2.0 μg/ml had a much higher mortality incidence than those with levels ≤2.0 μg/ml (HR 51.5), 1 where the HR was 18.4 in D-dimers ≥1.0 μg/ml. 2 Also, D-dimers were able to distinguish patients with moderate ...

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  • D-dimer in COVID-19: A Guide With Pitfalls :

    2020-6-7 · Survival odds with a normal day 1 D-dimer were 5.9 (95% CI = 3.6% to 9.7%); for a normal day 3 D-dimer, survival odds were 15.6 (95% CI = 7.7% to 31.8%). Association of coagulopathy with COVID-19 is now widely reported. 1 , 2 In the United States and elsewhere, rapid results of PCR coronavirus testing are not widely available and a positive ...

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  • High D-dimer levels are associated with poor

    As D-dimer plasma levels are elevated after clot formation, the measurement of D-dimer is routinely used in conjunction with clinical parameters in the initial assessment of suspected acute VTE. 8 Elevated D-dimer levels may also be observed in other clinical settings, such as cancer, pregnancy and infectious diseases or following trauma and ...

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  • The Clinical Usefulness of D-Dimer Testing in Cancer ...

    2011-9-1 · From my analysis of the literature, I draw the following conclusions. (a) d-dimer, as measured by a sensitive test, can be safely used to exclude VTE in symptomatic outpatients, provided that it is used in combination with the pretest clinical probability.(b) High concentrations of d-dimer are associated with an increased risk of recurrent VTE.(c) Patients who present with d-dimer above cutoff ...

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  • d-Dimer Testing in Laboratory Practice | Clinical ...

    2020-4-30 · Two patients had increases in D-dimer levels, and the third patient was admitted with a highly increased D-dimer level. Autopsy reports from COVID-19 patients have shown microthrombi in lungs and in other organs with associated foci of hemorrhage ( 3 , 4 ).

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  • Pulmonary Embolism and Increased Levels of D-Dimer

    2008-5-1 · The pooled sensitivity of the D-dimer test for patients with acute aortic dissection was 327/349, or 94% (95% CI 91–96). Including only those studies in which all acute aortic dissection patients had the D-dimer test, the sensitivity analysis revealed a test sensitivity of 183/192, or 95% (95% CI 91–98) (7, 9, 10, 12, 13, 15). The ...

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  • Serum D-Dimer is a Sensitive Test for the Detection of ...

    2021-6-15 · A high D-dimer at admission was an independent predictor for mortality in COVID-19 patients from Wuhan. Patients with a D-dimer ≥2.0 μg/ml had a much higher mortality incidence than those with levels ≤2.0 μg/ml (HR 51.5), 1 where the HR was 18.4 in D-dimers ≥1.0 μg/ml. 2 Also, D-dimers were able to distinguish patients with moderate ...

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  • D-dimer in COVID-19: A Guide With Pitfalls :

    Quest Diagnostics Location. The D-dimer blood test is used to detect D-Dimer in the bloodstream. When one gets injured got any cut, blood clumps up /clotting takes place. Blood clotting is an important part of healing that prevents one from losing too much blood during a body injury. The body doesn’t need any blood clots once the bleeding stops.

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  • D-Dimer Blood Test | Lab Testing API

    2020-7-10 · The distributions of D-dimer levels among patients with different clinical staging, chest CT staging, and who survived and deceased during hospitalization are presented in Figs. 1, 2, 3, and 4.On admission, D-dimer levels significantly increased with increasing severity of COVID-19 as determined by clinical staging (Kendall’s tau-b = 0.374, P = 0.000), chest CT staging (Kendall’s tau-b = 0 ...

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  • D-dimer as a biomarker for disease severity and

    Utility of D-Dimer in the Diagnosis of Patients with Chronic Thromboembolic Pulmonary Hypertension Vichaya Arunthari *, Charles D Burger. Division of Pulmonary Medicine, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL 32224, USA. Abstract.

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